14D2I61 - Pathology

Course specification
Course titlePathology
Type of studyPhD academic studies
Lecturer (for classes)
  1. prof. dr Sanja Aleksić-Kovačević
  2. prof. dr Darko Marinković
  3. prof. dr Vladimir Kukolj
  4. doc. dr Ivana Vučićević
Lecturer/Associate (for practice)
    Lecturer/Associate (for OTC)
      ConditionTo enroll semester in which the subject is attended
      The goalTo deepen the knowledge of mechanisms and morphology of basic pathological processes with emphasis on sublethal and lethal damage, circulatory disorders, inflammation, adaptation growth, oncology and teratology. To become familiar with peculiarities and comparative differences of pathological processes in different organ systems related to immunological, genetic and metabolic disorders and infective agents.
      The outcomeStudent should acquire knowledge and skills which will enable individual diagnostic work and scientific research in the field of pathology.
      Contents of lecturesSublethal and lethal cell damage. Cell death criteria. Changes of the cell organelles, cytoplasm and extracellular matrix. Forms and outcome of necrosis. Apoptosis. Hyperemia. Plethora. Hemorrhage. Ischemia. Infarctus. Trombosis. Disseminated intravascular coagulation. Embolia. Metastasis. Disorders of microcirculation. Disorders comprising leucocytes. Chemical mediators of inflammation. Forms and characteristics of acute inflammation. Infective granulomas. Regeneration. Organization. Wound healing. Factors of tissue regeneration. Immunodeficiencies. Autoimmune diseases. Etiology, growth and metastasis of tumors. Immunological reaction on tumor presence. Frequency and tumor occurrence. Nomenclature and systematics of tumors. Pathology of intestinal system, liver, biliary system and exocrine pancreas. Pathology of respiratory system. Pathology of heart and blood vessels. Pathology of hematopoietic system. Pathology of bones, joints and muscles. Pathology of nervous system. Pathology of reproductive system. Skin pathology. Practical lectures in histopathology and immunohistochemistry. Sampling techniques. Fixative choices. Preparations for staining. Methods of histochemical staining. Molecular methods in pathology. Necropsy and necropsy protocol. Descriptive pathology. Digital photography.
      Contents of exercisesWork in the necropsy room, preparation and analysis of histology slides.
      1. Milijana Knežević and Milijan Jovanović, General Pathology, Belgrade, 1999, Makarije
      2. Jovanović Milijan, Aleksić-Kovačević Sanja, Knežević Milijana, Special Veterinary Pathology, Second edition, 2019, Serbian Society of Veterinary Pathologists
      3. Donald McGavin M, James Zachary F, Pathologic basis of veterinary disease, (Original title)
      4. Jubb KVF, Peter Kennedy C, Palmer Nigel, Pathology of Domestic Animals, Academic Press, Inc. ISBN 0-12-391602-X, 1993 (Original title)
      5. Donald Meuten J, Tumors in domestic animals (Original title)
      6. Marinković Darko, Nešić Vladimir, Necropsy technique with thanatology - basics handbook, 2013, Facuty of Veterinary Medicine University of Belgrade, Belgrade
      7. Nešić Slađan, Vučićević Ivana, Handbook of histopathology for students of Facuty of Veterinary Medicine, 2018, Naučna KMD, Belgrade
      Number of hours per week during the semester/trimester/year
      LecturesExercisesOTCStudy and ResearchOther classes
      Methods of teachingTheoretical lectures, practical lectures, essay preparation, essay presentation, class presentation
      Knowledge score (maximum points 100)
      Pre obligationsPointsFinal examPoints
      Activites during lectures10Test paper70
      Practical lessons0Oral examination0